NeuroStar® TMS Therapy
FDA-cleared, non-medication depression treatment
(855) 940-4867
Medically reviewed on 11/13/2020 by
Dr. Steven Harvey
St. Louis Regional Medical Director
For some people, finding the right treatment for depression can be challenging. Although antidepressants and talk therapy work for many, they provide little to no relief for others. If you fall into the latter category, it's possible that you've wondered what happens if depression goes untreated. Will it go away, or will it get worse?
If you've found your antidepressants to be ineffective or produce too many unpleasant side effects, you may also be wondering what happens if you stop taking your antidepressants. Plus, you may be feeling discouraged with depression treatments in general and wonder if there's any point continuing the search. Is there any depression treatment out there that could be effective for you? The answer to that final question is a resounding "yes." There is always another option to try, even if medication and talk therapy haven't worked for you in the past. Let's take a look at why it's so important to treat depression, and what you can do if past treatments haven't been successful.
Depression (and the distressing feelings it can cause) often becomes more intense when it's left untreated. It can even become chronic and last for years or a lifetime. Depression doesn't only affect mood and emotions, either. Depression also causes physical symptoms such as nausea, chronic pain, fatigue, and headaches. And when it isn't treated, these symptoms persist. Sleep is affected, as well. Many people with untreated depression suffer insomnia and find it difficult to sleep. Others feel excessively tired and find it necessary to sleep more.
Some researchers believe that depression is connected to the immune system, so untreated depression may also impact your overall health or ability to recover from illnesses. Your personal, family, and work life could be impacted, too. For instance, if depression goes untreated, there's an increased likelihood of work performance decline and absenteeism.
Further, untreated depression has been found to increase a person's risk of developing drug or alcohol addiction. So, although it may be tempting to stop the search for treatment altogether, the negative consequences aren't worth it. In the long run, continuing to seek treatment will have the most positive results, even if it seems like a difficult road.
If you've found no relief from antidepressants, or if your antidepressants have had unpleasant side effects, you may be wondering, what happens if I stop taking my antidepressants? You may think it makes sense to stop taking something that just isn't working, but suddenly going off an antidepressant can have adverse outcomes. How? Put simply, antidepressants impact your brain chemistry. They work by changing the way certain brain chemicals, called neurotransmitters, affect your mood and emotion. Eventually, messenger cells in your brain get accustomed to receiving increased levels of neurotransmitters.
If you abruptly stop taking your antidepressants, you could experience serious symptoms of withdrawal—especially if you've taken the medication(s) for more than a month. Some of the withdrawal symptoms include nausea, anxiety, restlessness, trouble sleeping, nightmares, sweating, and electric shock-like feelings in your head. Altogether, these symptoms are also known as antidepressant discontinuation syndrome. Antidepressant withdrawal symptoms typically occur within a few days of stopping antidepressant medication. Generally, they can last for up to six weeks. In some cases, however, the withdrawal symptoms are more severe and can last for many months.
If you want to stop taking your antidepressant medication, you should speak to your physician first. Any reduction of your antidepressants will probably be gradual—over several weeks. This way, your body can adapt better to the changes in your neurotransmitter levels.
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If you've tried multiple antidepressant medications and feel like they aren't working, there's a chance you might have treatment-resistant depression. You're not alone, though: about one-third of people with depression still have symptoms even after trying two medications. It's also possible that the antidepressant you're on works well but has intolerable side effects. The search for the right treatment can take some time, but there are other options out there that have worked for many people.
Transcranial magnetic stimulation (TMS) therapy is one such option you may want to consider. It's a safe, non-invasive treatment that is used to effectively treat major depressive disorder. TMS therapy uses magnetic pulses to stimulate specific brain regions involved in mood regulation. It has successfully treated depression for many people who did not have much success with antidepressants and talk therapy. You can learn more about TMS therapy from patients reporting their positive outcomes. Whatever path you choose, remember to stay hopeful on your journey. You deserve to feel like yourself again.
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NeuroStar Adult Indications for Use
The NeuroStar Advanced Therapy System is indicated for the treatment of depressive episodes and for decreasing anxiety symptoms for those who may exhibit comorbid anxiety symptoms in adult patients suffering from Major Depressive Disorder (MDD) and who failed to achieve satisfactory improvement from previous antidepressant medication treatment in the current episode.
The NeuroStar Advanced Therapy System is intended to be used as an adjunct for the treatment of adult patients suffering from Obsessive-Compulsive Disorder (OCD).
NeuroStar Adolescent Indications for Use
NeuroStar Advanced Therapy is indicated as an adjunct for the treatment of Major Depressive Disorder (MDD) in adolescent patients (15-21).
Important Safety Information
NeuroStar Advanced Therapy is only available by prescription. A doctor can help decide if NeuroStar Advanced Therapy is right for you. Patients’ results may vary.
The most common side effect is pain or discomfort at or near the treatment site. These events are transient; they occur during the TMS treatment course and do not occur for most patients after the first week of treatment. There is a rare risk of seizure associated with the use of TMS therapy (<0.1% per patient).
Visit neurostar.com for full safety and prescribing information.
Important Safety Information
What is the most important information I should know about SPRAVATO®?
SPRAVATO® can cause serious side effects, including:
Do not take SPRAVATO® if you:
If you are not sure if you have any of the above conditions, talk to your healthcare provider before taking SPRAVATO®.
Before you take SPRAVATO®, tell your healthcare provider about all of your medical conditions, including if you:
Tell your healthcare provider about all the medicines that you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. Taking SPRAVATO® with certain medicine may cause side effects.
Especially tell your healthcare provider if you take central nervous system (CNS) depressants, psychostimulants, or monoamine oxidase inhibitors (MAOIs) medicine. Keep a list of them to show to your healthcare provider and pharmacist when you get a new medicine.
How will I take SPRAVATO®?
What should I avoid while taking SPRAVATO®?
Do not drive, operate machinery, or do anything where you need to be completely alert after taking SPRAVATO®. Do not take part in these activities until the next day following a restful sleep. See “What is the most important information I should know about SPRAVATO®?”
What are the possible side effects of SPRAVATO®?
SPRAVATO® may cause serious side effects including:
See “What is the most important information I should know about SPRAVATO®?”
Increased blood pressure. SPRAVATO® can cause a temporary increase in your blood pressure that may last for about 4 hours after taking a dose. Your healthcare provider will check your blood pressure before taking SPRAVATO® and for at least 2 hours after you take SPRAVATO®. Tell your healthcare provider right away if you get chest pain, shortness of breath, sudden severe headache, change in vision, or seizures after taking SPRAVATO®.
Problems with thinking clearly. Tell your healthcare provider if you have problems thinking or remembering.
Bladder problems. Tell your healthcare provider if you develop trouble urinating, such as a frequent or urgent need to urinate, pain when urinating, or urinating frequently at night.
The most common side effects of SPRAVATO® include:
If these common side effects occur, they usually happen right after taking SPRAVATO® and go away the same day.
These are not all the possible side effects of SPRAVATO®.
Call your doctor for medical advice about side effects. You may report side effects to Johnson & Johnson at 1-800-526-7736, or to the FDA at 1-800-FDA-1088.
What is SPRAVATO® (esketamine) CIII nasal spray?
SPRAVATO® is a prescription medicine used:
SPRAVATO® is not for use as a medicine to prevent or relieve pain (anesthetic). It is not known if SPRAVATO® is safe or effective as an anesthetic medicine.
It is not known if SPRAVATO® is safe and effective for use in preventing suicide or in reducing suicidal thoughts or actions. SPRAVATO® is not for use in place of hospitalization if your healthcare provider determines that hospitalization is needed, even if improvement is experienced after the first dose of SPRAVATO®.
It is not known if SPRAVATO® is safe and effective in children.
Please see full Prescribing Information, including Boxed WARNINGS, and Medication Guide for SPRAVATO® and discuss any questions you may have with your healthcare provider.
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