NeuroStar® TMS Therapy
FDA-cleared, non-medication depression treatment
(855) 940-4867
Medically reviewed on 11/16/2020 by
Dr. Geoffrey Grammer
Chief Medical Officer
If you've been negotiating a chronic illness day after day, you're bound to feel run down at times. Long-lasting illnesses such as diabetes or Parkinson's disease can cause incessant pain and stress. They can also make it difficult or sometimes impossible to function at your best at work and in your relationships. But those illnesses can also trigger another condition: depression. Chronic illness and depression often go hand in hand, each making the other worse. So, managing your chronic illness and taking care of your mental health is ultimately a double-duty job. According to the Cleveland Clinic, one-third of people with chronic illnesses also experience depression. There's a medical term for this: "comorbidity," the simultaneous presence of two or more distinct conditions in a patient. The symptoms of one condition can often overlap with and mask another. This can make it difficult for people with depression (and sometimes even their doctors) to recognize that two separate ailments—each requiring its own treatment—are occurring at the same time. The list of illnesses that persist or can't be fully cured is unfortunately long. Along with physical pains, chronic conditions like cancer, AIDS/HIV, and multiple sclerosis can bring emotional ones, too, from fear to frustration and loneliness. It's no wonder that the continuous stress of a chronic illness can affect your mental health. Still, it's important to recognize that you are not alone, and that there is hope.
A problem can arise when patients and physicians fail to recognize that certain normal and expected feelings have reached the threshold of triggering medical depression. Treating the chronic illness can take so much attention and energy that it's easy to overlook another condition in the midst. To complicate matters, many of the telltale symptoms of depression are the same ones that people with chronic illnesses experience: fatigue, insomnia, stomach troubles, backaches and headaches, weight gain or loss, sexual dysfunction, problems concentrating, and feelings of helplessness, worthlessness, or hopelessness. It can be hard to distinguish whether these symptoms are caused by chronic illness or by depression. The cause could, in fact, be both. Many of the physical symptoms brought about by depression are associated with inflammation in the body, potentially leading to aches and pains, a weakened immune system, and increased stress. All of these can worsen chronic illness, which in turn can heighten depression. Research has shown, for example, that depression is associated with poorer prognoses and faster development of chronic illnesses, such as heart disease and diabetes. Chronic illness and depression have a cyclical, mutually harmful relationship, each one exacerbating the other.
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Depression is associated with changes in the brain chemicals that regulate signaling and moods. For some people, it can be effectively treated with talk therapy and/or antidepressants and other medications. Yet roughly one in three people don't find relief even after trying two medications. And if you have a chronic condition that already requires medications, you simply may not want to add another pill for depression. You might also be concerned about potential drug interactions between a chronic illness medication and depression medications—or that your chronic illness medication may actually be increasing your risk for or contributing to depression. Especially if you fall into these categories, Transcranial Magnetic Stimulation (TMS) is a depression treatment worth considering. TMS is a non-invasive, drug-free, outpatient treatment in which you sit in a comfortable chair, awake and alert, while a device near your scalp delivers gentle magnetic pulses. These pulses, similar to those in an MRI scan, stimulate changes in brain chemical signaling that can alleviate symptoms of Major Depressive Disorder. To learn more about whether TMS therapy is right for you, schedule a no-cost consultation. If you have a chronic illness, keep in mind that you also have a higher risk of depression. While it can be tough to do, it's important to take care of both your chronic illness and your mental health. You deserve to feel your best, and treatment can help get you there.
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NeuroStar Adult Indications for Use
The NeuroStar Advanced Therapy System is indicated for the treatment of depressive episodes and for decreasing anxiety symptoms for those who may exhibit comorbid anxiety symptoms in adult patients suffering from Major Depressive Disorder (MDD) and who failed to achieve satisfactory improvement from previous antidepressant medication treatment in the current episode.
The NeuroStar Advanced Therapy System is intended to be used as an adjunct for the treatment of adult patients suffering from Obsessive-Compulsive Disorder (OCD).
NeuroStar Adolescent Indications for Use
NeuroStar Advanced Therapy is indicated as an adjunct for the treatment of Major Depressive Disorder (MDD) in adolescent patients (15-21).
Important Safety Information
NeuroStar Advanced Therapy is only available by prescription. A doctor can help decide if NeuroStar Advanced Therapy is right for you. Patients’ results may vary.
The most common side effect is pain or discomfort at or near the treatment site. These events are transient; they occur during the TMS treatment course and do not occur for most patients after the first week of treatment. There is a rare risk of seizure associated with the use of TMS therapy (<0.1% per patient).
Visit neurostar.com for full safety and prescribing information.
Important Safety Information
What is the most important information I should know about SPRAVATO®?
SPRAVATO® can cause serious side effects, including:
Do not take SPRAVATO® if you:
If you are not sure if you have any of the above conditions, talk to your healthcare provider before taking SPRAVATO®.
Before you take SPRAVATO®, tell your healthcare provider about all of your medical conditions, including if you:
Tell your healthcare provider about all the medicines that you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. Taking SPRAVATO® with certain medicine may cause side effects.
Especially tell your healthcare provider if you take central nervous system (CNS) depressants, psychostimulants, or monoamine oxidase inhibitors (MAOIs) medicine. Keep a list of them to show to your healthcare provider and pharmacist when you get a new medicine.
How will I take SPRAVATO®?
What should I avoid while taking SPRAVATO®?
Do not drive, operate machinery, or do anything where you need to be completely alert after taking SPRAVATO®. Do not take part in these activities until the next day following a restful sleep. See “What is the most important information I should know about SPRAVATO®?”
What are the possible side effects of SPRAVATO®?
SPRAVATO® may cause serious side effects including:
See “What is the most important information I should know about SPRAVATO®?”
Increased blood pressure. SPRAVATO® can cause a temporary increase in your blood pressure that may last for about 4 hours after taking a dose. Your healthcare provider will check your blood pressure before taking SPRAVATO® and for at least 2 hours after you take SPRAVATO®. Tell your healthcare provider right away if you get chest pain, shortness of breath, sudden severe headache, change in vision, or seizures after taking SPRAVATO®.
Problems with thinking clearly. Tell your healthcare provider if you have problems thinking or remembering.
Bladder problems. Tell your healthcare provider if you develop trouble urinating, such as a frequent or urgent need to urinate, pain when urinating, or urinating frequently at night.
The most common side effects of SPRAVATO® include:
If these common side effects occur, they usually happen right after taking SPRAVATO® and go away the same day.
These are not all the possible side effects of SPRAVATO®.
Call your doctor for medical advice about side effects. You may report side effects to Johnson & Johnson at 1-800-526-7736, or to the FDA at 1-800-FDA-1088.
What is SPRAVATO® (esketamine) CIII nasal spray?
SPRAVATO® is a prescription medicine used:
SPRAVATO® is not for use as a medicine to prevent or relieve pain (anesthetic). It is not known if SPRAVATO® is safe or effective as an anesthetic medicine.
It is not known if SPRAVATO® is safe and effective for use in preventing suicide or in reducing suicidal thoughts or actions. SPRAVATO® is not for use in place of hospitalization if your healthcare provider determines that hospitalization is needed, even if improvement is experienced after the first dose of SPRAVATO®.
It is not known if SPRAVATO® is safe and effective in children.
Please see full Prescribing Information, including Boxed WARNINGS, and Medication Guide for SPRAVATO® and discuss any questions you may have with your healthcare provider.
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