NeuroStar® TMS Therapy
FDA-cleared, non-medication depression treatment
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Dr. Misty Borst joined Greenbrook TMS in November 2016 as Medical Director at our Columbia center in Maryland. Originally from South Carolina, Dr. Borst has worked in both inpatient and outpatient settings and has been treating patients with TMS since 2016. Dr. Borst is board certified in adult psychiatry and is a member of the American Psychiatric Association as well as the Maryland Psychiatric Society. Read on to learn about her thoughts on TMS therapy.
Once I was into my psychiatry rotation during medical school, I loved it. I loved the amount of gray area in psychiatry—For four patients, even if they all have depression, that depression was different in each of them. I really appreciated that the gray area felt artistic- a lot of thought had to be put into each particular person’s situation. I’m sure that’s true for all types of medicine, but it really resonated with me in the world of psychiatry.
The statistics are quite compelling. When you look at the success rates once a patient has tried a certain number of medications, TMS therapy is statistically a far better option for many depressed patients. In addition, TMS is personalized for each patient and as a treatment modality, it has so few side effects. Any psychiatrist should be interested in anything that is new and can help our patients.
If a person feels very depressed and the antidepressants work even a little bit, they are initially pleased with that because it is better than where they were. Over the course of months, some people will realize that it’s just not enough. Some people may feel somewhat better with the medication and get used to that and accept that this is their new normal, but it doesn’t necessarily have to be. They will say they’re fine, but we know from a clinical standpoint, there can be further improvement. We want them to be better than fine.
Generally, we keep people on the same medications they were on prior to starting TMS therapy unless they were having a particular side effect and want to be off a medication. In general if a person does well with TMS and gets a good response, I recommend they wait a few months to see things are remaining as they want them to be. Then, if they want to try decreasing their medication, that is a perfectly okay time to talk with their doctor about it.
People will notice the patient looks a little brighter or less weighed down. Once the treatment starts working, when someone walks into the office, we can get a sense that things are starting to turn around. Throughout the course of treatment, the physical manifestations of depression will start to change: a patient’s sleep will improve, their energy and motivation will pick up. And they will start to feel relief from their sadness or hopelessness.
Seeing the changes in patients. I had a patient just last month who had tried many different antidepressants over the course of years and hadn’t had much success with any of them. Once he went through TMS Therapy, he was like a different person. A very happy, new person. He was bright, excited, and he recognized that he felt completely different and much better. His family saw it, too.
Many people find it a little daunting that treatments are five days a week for several weeks. Then they are surprised when they find themselves looking forward to TMS sessions each day. Patients like taking a break from their day and having time where outside stressors can’t get to them. During treatment they can reliably get away from everything and they don’t mind it as much as they thought they would. The sessions are fairly quick, patients can drive themselves, and they can get in and out efficiently.
Depression can certainly affect everything in a negative way. I see patients who end up just spending their time after work in their bedroom instead of hanging out with their kids. It can diminish relationships between parents and kids and can cause strain between spouses. Depression is great at facilitating distance between people. At work, depression can decrease a person’s productivity to the point where managers might notice. I’ve seen patients with depression become less able to tolerate stressors, so they’re getting irritable or snappy at a coworker when normally, if they weren’t depressed, they would be able to handle the stress and brush it off. All those little micro-insults are so much harder to handle if you’re depressed.
If you notice a friend or family member isn’t wanting to hang out as much, if they aren’t as social or if they are isolating, those are signs something is going on with them and maybe they are struggling. If they look more disheveled or are having major changes with their sleep or their weight, those can be more obvious signs. But socially and emotionally, if they seem like they aren’t themselves that’s enough to warrant concern. If you’re worried about someone, you can start by asking how that person is doing. You might have to persist a little bit in asking. Sometimes you have to risk having an awkward conversation or feeling a little uncomfortable to pull it out of a person. Maybe they’re okay, or maybe it’s something else, but it’s worth double checking.
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NeuroStar Adult Indications for Use
The NeuroStar Advanced Therapy System is indicated for the treatment of depressive episodes and for decreasing anxiety symptoms for those who may exhibit comorbid anxiety symptoms in adult patients suffering from Major Depressive Disorder (MDD) and who failed to achieve satisfactory improvement from previous antidepressant medication treatment in the current episode.
The NeuroStar Advanced Therapy System is intended to be used as an adjunct for the treatment of adult patients suffering from Obsessive-Compulsive Disorder (OCD).
NeuroStar Adolescent Indications for Use
NeuroStar Advanced Therapy is indicated as an adjunct for the treatment of Major Depressive Disorder (MDD) in adolescent patients (15-21).
Important Safety Information
NeuroStar Advanced Therapy is only available by prescription. A doctor can help decide if NeuroStar Advanced Therapy is right for you. Patients’ results may vary.
The most common side effect is pain or discomfort at or near the treatment site. These events are transient; they occur during the TMS treatment course and do not occur for most patients after the first week of treatment. There is a rare risk of seizure associated with the use of TMS therapy (<0.1% per patient).
Visit neurostar.com for full safety and prescribing information.
Important Safety Information
What is the most important information I should know about SPRAVATO®?
SPRAVATO® can cause serious side effects, including:
Do not take SPRAVATO® if you:
If you are not sure if you have any of the above conditions, talk to your healthcare provider before taking SPRAVATO®.
Before you take SPRAVATO®, tell your healthcare provider about all of your medical conditions, including if you:
Tell your healthcare provider about all the medicines that you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. Taking SPRAVATO® with certain medicine may cause side effects.
Especially tell your healthcare provider if you take central nervous system (CNS) depressants, psychostimulants, or monoamine oxidase inhibitors (MAOIs) medicine. Keep a list of them to show to your healthcare provider and pharmacist when you get a new medicine.
How will I take SPRAVATO®?
What should I avoid while taking SPRAVATO®?
Do not drive, operate machinery, or do anything where you need to be completely alert after taking SPRAVATO®. Do not take part in these activities until the next day following a restful sleep. See “What is the most important information I should know about SPRAVATO®?”
What are the possible side effects of SPRAVATO®?
SPRAVATO® may cause serious side effects including:
See “What is the most important information I should know about SPRAVATO®?”
Increased blood pressure. SPRAVATO® can cause a temporary increase in your blood pressure that may last for about 4 hours after taking a dose. Your healthcare provider will check your blood pressure before taking SPRAVATO® and for at least 2 hours after you take SPRAVATO®. Tell your healthcare provider right away if you get chest pain, shortness of breath, sudden severe headache, change in vision, or seizures after taking SPRAVATO®.
Problems with thinking clearly. Tell your healthcare provider if you have problems thinking or remembering.
Bladder problems. Tell your healthcare provider if you develop trouble urinating, such as a frequent or urgent need to urinate, pain when urinating, or urinating frequently at night.
The most common side effects of SPRAVATO® include:
If these common side effects occur, they usually happen right after taking SPRAVATO® and go away the same day.
These are not all the possible side effects of SPRAVATO®.
Call your doctor for medical advice about side effects. You may report side effects to Johnson & Johnson at 1-800-526-7736, or to the FDA at 1-800-FDA-1088.
What is SPRAVATO® (esketamine) CIII nasal spray?
SPRAVATO® is a prescription medicine used:
SPRAVATO® is not for use as a medicine to prevent or relieve pain (anesthetic). It is not known if SPRAVATO® is safe or effective as an anesthetic medicine.
It is not known if SPRAVATO® is safe and effective for use in preventing suicide or in reducing suicidal thoughts or actions. SPRAVATO® is not for use in place of hospitalization if your healthcare provider determines that hospitalization is needed, even if improvement is experienced after the first dose of SPRAVATO®.
It is not known if SPRAVATO® is safe and effective in children.
Please see full Prescribing Information, including Boxed WARNINGS, and Medication Guide for SPRAVATO® and discuss any questions you may have with your healthcare provider.
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