NeuroStar® TMS Therapy
FDA-cleared, non-medication depression treatment
(855) 940-4867
Medically reviewed on 12/13/2020 by
Dr. Darlene Ifill-Taylor
Charlotte Regional Medical Director
Say you have a boss who puts you down so constantly that your emotional health starts to suffer. After one particularly tough exchange, you close your laptop and set off for a 10-mile run. Back home, your feelings have lost their edge and you spend the afternoon productively. In this case, exercise had a clear effect on your mood—but what if your sadness and difficulty making decisions persist for weeks or months? Can exercise help with depression? The simple answer is yes. Research has shown the positive effects of exercise on depression. For some people, exercise can complement other therapies and help improve symptoms of depression. But like many other strategies for alleviating depression, exercise doesn't help everyone, and it isn't a one-stop cure or a replacement for professional treatment.
There are many theories about the benefits of exercise for depression. Some effects of exercise on depression are psychological and emotional: Exercise can distract you from your worries. It can give you a sense of control and boost your self-confidence and self-esteem. Studies have also demonstrated that exercise has beneficial physiological effects. It can increase levels of certain chemicals in the brain, including endorphins, which reduce pain, and neurotransmitters, which enhance signaling between brain cells.
Exercise also stimulates muscles to secrete chemicals that increase levels of a protein called brain-derived neurotrophic factor, or BDNF, which is essential for growing and maintaining healthy brain cells. Increasing the levels of these chemicals counteracts the impacts of depression, which is associated with impeded signaling in areas of the brain that regulate mood. To benefit from exercise, you don't have to go all out running, swimming, biking, or lifting weights. Low-intensity exercises such as yoga and stretching can be effective, too. Even minor exercise can help. Try something more manageable for you, such as gardening, housework, taking a walk, or using the stairs instead of the elevator.
But if exercise feels like too much for you, don't worry. It doesn't mean you're lazy. Remember that depression is a medical condition that saps your energy and impairs your ability to focus, feel motivated, and act on plans. After you get treatment for depression, you can identify the best way to slowly add exercise into your tool kit of strategies to maintain your overall well-being.
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The most important step is to seek treatment from mental health professionals. They can offer a variety of therapies that successfully relieve the symptoms of depression. Most frequent among first-line treatment strategies are talk therapy (Interpersonal, Psychodynamic or cognitive behavioral therapy) and antidepressant medications. But just as exercise itself isn't a silver bullet for depression, roughly 1 in 3 people don't experience relief even after trying two medications. If you've struggled to find an effective depression treatment, consider Transcranial Magnetic Stimulation (TMS) therapy.
TMS is a non-invasive, drug-free treatment in which a device near your scalp delivers gentle magnetic pulses, similar to those in an MRI scan. You sit comfortably during the session, remaining awake and alert. The pulses stimulate changes in brain chemical signaling that can alleviate symptoms of Major Depressive Disorder. TMS is FDA-cleared for those who have tried one medication without success (and covered by most insurance policies after two medications). Depression affects different people in different ways. Some treatments work for some individuals, but not for others. Finding the right option for you is critical for both your mental and your physical health, especially if it helps you enjoy and engage in regular exercise. To learn more about whether TMS is right for you, schedule a no-cost consultation.
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NeuroStar Adult Indications for Use
The NeuroStar Advanced Therapy System is indicated for the treatment of depressive episodes and for decreasing anxiety symptoms for those who may exhibit comorbid anxiety symptoms in adult patients suffering from Major Depressive Disorder (MDD) and who failed to achieve satisfactory improvement from previous antidepressant medication treatment in the current episode.
The NeuroStar Advanced Therapy System is intended to be used as an adjunct for the treatment of adult patients suffering from Obsessive-Compulsive Disorder (OCD).
NeuroStar Adolescent Indications for Use
NeuroStar Advanced Therapy is indicated as an adjunct for the treatment of Major Depressive Disorder (MDD) in adolescent patients (15-21).
Important Safety Information
NeuroStar Advanced Therapy is only available by prescription. A doctor can help decide if NeuroStar Advanced Therapy is right for you. Patients’ results may vary.
The most common side effect is pain or discomfort at or near the treatment site. These events are transient; they occur during the TMS treatment course and do not occur for most patients after the first week of treatment. There is a rare risk of seizure associated with the use of TMS therapy (<0.1% per patient).
Visit neurostar.com for full safety and prescribing information.
Important Safety Information
What is the most important information I should know about SPRAVATO®?
SPRAVATO® can cause serious side effects, including:
Do not take SPRAVATO® if you:
If you are not sure if you have any of the above conditions, talk to your healthcare provider before taking SPRAVATO®.
Before you take SPRAVATO®, tell your healthcare provider about all of your medical conditions, including if you:
Tell your healthcare provider about all the medicines that you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. Taking SPRAVATO® with certain medicine may cause side effects.
Especially tell your healthcare provider if you take central nervous system (CNS) depressants, psychostimulants, or monoamine oxidase inhibitors (MAOIs) medicine. Keep a list of them to show to your healthcare provider and pharmacist when you get a new medicine.
How will I take SPRAVATO®?
What should I avoid while taking SPRAVATO®?
Do not drive, operate machinery, or do anything where you need to be completely alert after taking SPRAVATO®. Do not take part in these activities until the next day following a restful sleep. See “What is the most important information I should know about SPRAVATO®?”
What are the possible side effects of SPRAVATO®?
SPRAVATO® may cause serious side effects including:
See “What is the most important information I should know about SPRAVATO®?”
Increased blood pressure. SPRAVATO® can cause a temporary increase in your blood pressure that may last for about 4 hours after taking a dose. Your healthcare provider will check your blood pressure before taking SPRAVATO® and for at least 2 hours after you take SPRAVATO®. Tell your healthcare provider right away if you get chest pain, shortness of breath, sudden severe headache, change in vision, or seizures after taking SPRAVATO®.
Problems with thinking clearly. Tell your healthcare provider if you have problems thinking or remembering.
Bladder problems. Tell your healthcare provider if you develop trouble urinating, such as a frequent or urgent need to urinate, pain when urinating, or urinating frequently at night.
The most common side effects of SPRAVATO® include:
If these common side effects occur, they usually happen right after taking SPRAVATO® and go away the same day.
These are not all the possible side effects of SPRAVATO®.
Call your doctor for medical advice about side effects. You may report side effects to Johnson & Johnson at 1-800-526-7736, or to the FDA at 1-800-FDA-1088.
What is SPRAVATO® (esketamine) CIII nasal spray?
SPRAVATO® is a prescription medicine used:
SPRAVATO® is not for use as a medicine to prevent or relieve pain (anesthetic). It is not known if SPRAVATO® is safe or effective as an anesthetic medicine.
It is not known if SPRAVATO® is safe and effective for use in preventing suicide or in reducing suicidal thoughts or actions. SPRAVATO® is not for use in place of hospitalization if your healthcare provider determines that hospitalization is needed, even if improvement is experienced after the first dose of SPRAVATO®.
It is not known if SPRAVATO® is safe and effective in children.
Please see full Prescribing Information, including Boxed WARNINGS, and Medication Guide for SPRAVATO® and discuss any questions you may have with your healthcare provider.
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