NeuroStar® TMS Therapy
FDA-cleared, non-medication depression treatment
(855) 940-4867
Medically reviewed on 11/17/2020 by
Dr. Geoffrey Grammer
Chief Medical Officer
If you've noticed yourself losing or gaining weight while experiencing depression, you're not alone. It's not uncommon for depression to cause changes to appetite, along with a host of other physical symptoms like fatigue and digestive problems. In fact, nearly half of adults with depression experience the combined effects of depression and loss of appetite. Meanwhile, roughly 35 percent see an increased appetite related to depression and may find themselves eating more than normal.
This divergence means that the relationship between depression and appetite is a complex one. Here's a closer look at why depression might change how hungry you feel and where to look for support and treatment.
There's limited research into exactly why depression leads to appetite changes. However, one study using functional magnetic resonance imaging showed that similar parts of the brain are implicated in both depression and appetite cues. Different brain responses are associated with different changes in appetite, which could indicate that there are different subgroups of depression.
Beyond affecting your hunger levels, depression can influence the types of food you eat. It's common for people who are experiencing depression and feeling unmotivated to opt for quick and convenient meals or snacks. Similarly, the fatigue and lack of energy that often come with depression can make it difficult to feel like preparing and cooking healthy meals from scratch. If you have an increased appetite, you may crave comforting prepared foods. These are often high in sugar and addictive. As well as being an easy option, these foods may give you an initial feel-good buzz, boosting your mood and energy in the short term. However, they can also lead to energy slumps later, making you feel worse in the long run.
It's easy to see how depression and appetite changes can lead to a cycle of under- or overeating and reliance on convenient foods. We all know about the importance of eating a healthy, balanced diet to maintain your overall health and well-being. This is equally true when it comes to depression. Research shows a link between high-sugar diets and reduced mood. In fact, 95 percent of the mood-boosting chemical serotonin is produced in your gastrointestinal tract. What you put into your stomach really can make a difference to what happens inside your brain.
However, when you're experiencing depression, it can be difficult to muster the energy required to take control of your eating habits. This isn't your fault; remember that appetite changes are common with depression. But that doesn't mean you have to put up with them. Even if you're able to make some adjustments on your own, it's important to seek professional treatment for depression. This can set you on the path toward getting your appetite and diet back in balance as well as improving your mental health.
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Your first port of call will often be your doctor or health care team. They can listen to your concerns and recommend common first-line treatments such as antidepressant medications or talk therapy, which may help ease your symptoms. But we know that for some people, depression can be more persistent, and certain treatments may not be as effective for everyone. One study showed that even after trying two different medications, a third of people weren't free of depression symptoms. If previous treatments haven't helped you, Transcranial Magnetic Stimulation (TMS) therapy is a non-drug, non-invasive option to consider.
TMS is an FDA-cleared treatment for Major Depressive Disorder (MDD). It works by stimulating areas of the brain involved in mood regulation, so it could help to get both your mental health and your appetite back on track. To learn more about TMS and whether it might be right for you, schedule a no-cost consultation.
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NeuroStar Adult Indications for Use
The NeuroStar Advanced Therapy System is indicated for the treatment of depressive episodes and for decreasing anxiety symptoms for those who may exhibit comorbid anxiety symptoms in adult patients suffering from Major Depressive Disorder (MDD) and who failed to achieve satisfactory improvement from previous antidepressant medication treatment in the current episode.
The NeuroStar Advanced Therapy System is intended to be used as an adjunct for the treatment of adult patients suffering from Obsessive-Compulsive Disorder (OCD).
NeuroStar Adolescent Indications for Use
NeuroStar Advanced Therapy is indicated as an adjunct for the treatment of Major Depressive Disorder (MDD) in adolescent patients (15-21).
Important Safety Information
NeuroStar Advanced Therapy is only available by prescription. A doctor can help decide if NeuroStar Advanced Therapy is right for you. Patients’ results may vary.
The most common side effect is pain or discomfort at or near the treatment site. These events are transient; they occur during the TMS treatment course and do not occur for most patients after the first week of treatment. There is a rare risk of seizure associated with the use of TMS therapy (<0.1% per patient).
Visit neurostar.com for full safety and prescribing information.
Important Safety Information
What is the most important information I should know about SPRAVATO®?
SPRAVATO® can cause serious side effects, including:
Do not take SPRAVATO® if you:
If you are not sure if you have any of the above conditions, talk to your healthcare provider before taking SPRAVATO®.
Before you take SPRAVATO®, tell your healthcare provider about all of your medical conditions, including if you:
Tell your healthcare provider about all the medicines that you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. Taking SPRAVATO® with certain medicine may cause side effects.
Especially tell your healthcare provider if you take central nervous system (CNS) depressants, psychostimulants, or monoamine oxidase inhibitors (MAOIs) medicine. Keep a list of them to show to your healthcare provider and pharmacist when you get a new medicine.
How will I take SPRAVATO®?
What should I avoid while taking SPRAVATO®?
Do not drive, operate machinery, or do anything where you need to be completely alert after taking SPRAVATO®. Do not take part in these activities until the next day following a restful sleep. See “What is the most important information I should know about SPRAVATO®?”
What are the possible side effects of SPRAVATO®?
SPRAVATO® may cause serious side effects including:
See “What is the most important information I should know about SPRAVATO®?”
Increased blood pressure. SPRAVATO® can cause a temporary increase in your blood pressure that may last for about 4 hours after taking a dose. Your healthcare provider will check your blood pressure before taking SPRAVATO® and for at least 2 hours after you take SPRAVATO®. Tell your healthcare provider right away if you get chest pain, shortness of breath, sudden severe headache, change in vision, or seizures after taking SPRAVATO®.
Problems with thinking clearly. Tell your healthcare provider if you have problems thinking or remembering.
Bladder problems. Tell your healthcare provider if you develop trouble urinating, such as a frequent or urgent need to urinate, pain when urinating, or urinating frequently at night.
The most common side effects of SPRAVATO® include:
If these common side effects occur, they usually happen right after taking SPRAVATO® and go away the same day.
These are not all the possible side effects of SPRAVATO®.
Call your doctor for medical advice about side effects. You may report side effects to Johnson & Johnson at 1-800-526-7736, or to the FDA at 1-800-FDA-1088.
What is SPRAVATO® (esketamine) CIII nasal spray?
SPRAVATO® is a prescription medicine used:
SPRAVATO® is not for use as a medicine to prevent or relieve pain (anesthetic). It is not known if SPRAVATO® is safe or effective as an anesthetic medicine.
It is not known if SPRAVATO® is safe and effective for use in preventing suicide or in reducing suicidal thoughts or actions. SPRAVATO® is not for use in place of hospitalization if your healthcare provider determines that hospitalization is needed, even if improvement is experienced after the first dose of SPRAVATO®.
It is not known if SPRAVATO® is safe and effective in children.
Please see full Prescribing Information, including Boxed WARNINGS, and Medication Guide for SPRAVATO® and discuss any questions you may have with your healthcare provider.
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