NeuroStar® TMS Therapy
FDA-cleared, non-medication depression treatment
(855) 940-4867
Medically reviewed on 11/16/2020 by
Dr. Kimberly Cress
Texas Regional Medical Director
Everyone's experience with depression is unique. But studies of men and depression reveal some general trends in how depression affects males and females differently. The causes of depression in men and women may be similar, but they may experience different symptoms and cope in differing ways. Men, their families, and their doctors may not immediately recognize the signs that they are depressed, so they may be less inclined to seek treatment.
For these reasons, they may be less likely to be diagnosed and treated for depression and continue to suffer needlessly. These factors may influence the reportedly higher incidence of depression among females (8.7 percent) compared to males (5.3 percent) in the United States population; it's possible that men are more often undiagnosed. According to a Journal of the American Medical Association Psychiatry study in 2013, nearly one-third of U.S. men (30.6 percent) experience depression in their lifetimes.
Are the causes of depression in men and women different? No. Both men and women can have underlying genetics and family histories that increase their susceptibility. Depression in men and women can be triggered by stress and/or grief from setbacks and losses in life, including illness, abuse, poverty, family conflicts, and losing loved ones or jobs. Older men who retire may experience a sudden loss of routine, power, and prestige that can diminish their self-esteem and cause depression. Remember that it's possible to develop depression without anything being "wrong" in a person's life. Depression causes many similar physical symptoms in men and women such as fatigue, sleep and eating problems, chronic pains, headaches, or digestive ailments. Both genders can also experience similar feelings of sadness, helplessness, hopelessness, guilt, and worthlessness.
However, our culture puts a stigma on men being emotional. Unlike women, many men are socially conditioned to bottle up their negative feelings or those that are seen as feminine. As a consequence, depressed men can become irritable, frustrated, and angry. They often deal with depression by working compulsively or engaging in rash behaviors, such as drinking too much, taking drugs, gambling, smoking, having unsafe sex, and reckless driving. They may not acknowledge that the physical ailments they are suffering—backaches, headaches, sleep problems, digestion problems, or sexual dysfunction—may be rooted in depression. Men are also three times more likely to die by suicide than women are. The way men experience depression masks it from themselves, their family, and their friends. Sometimes, even medical professionals overlook depression symptoms in men. Even if men recognize and acknowledge that they are depressed, the unfortunate stigma that depression is somehow "unmanly" can deter men from seeking treatment.
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Why let depression diminish the quality of your life? Various therapies, such as talk therapy and cognitive behavioral therapy, have brought relief to many men and helped them overcome depression and lead more fulfilling lives. Many people's symptoms are relieved by medications that adjust brain chemistry and functioning. Another option you may not have heard about is transcranial magnetic stimulation (TMS). This non-invasive, non-drug treatment uses magnetic pulses to improve brain signaling that regulates your mood. If you've already tried multiple therapies with disappointing results, TMS therapy may be right for you. As studies on men and depression have shown, they experience the same underlying condition as anyone else, but it can manifest differently. Learning what depression can look like in men, and acknowledging what you may be experiencing, is the first step to feeling yourself again.
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NeuroStar Adult Indications for Use
The NeuroStar Advanced Therapy System is indicated for the treatment of depressive episodes and for decreasing anxiety symptoms for those who may exhibit comorbid anxiety symptoms in adult patients suffering from Major Depressive Disorder (MDD) and who failed to achieve satisfactory improvement from previous antidepressant medication treatment in the current episode.
The NeuroStar Advanced Therapy System is intended to be used as an adjunct for the treatment of adult patients suffering from Obsessive-Compulsive Disorder (OCD).
NeuroStar Adolescent Indications for Use
NeuroStar Advanced Therapy is indicated as an adjunct for the treatment of Major Depressive Disorder (MDD) in adolescent patients (15-21).
Important Safety Information
NeuroStar Advanced Therapy is only available by prescription. A doctor can help decide if NeuroStar Advanced Therapy is right for you. Patients’ results may vary.
The most common side effect is pain or discomfort at or near the treatment site. These events are transient; they occur during the TMS treatment course and do not occur for most patients after the first week of treatment. There is a rare risk of seizure associated with the use of TMS therapy (<0.1% per patient).
Visit neurostar.com for full safety and prescribing information.
Important Safety Information
What is the most important information I should know about SPRAVATO®?
SPRAVATO® can cause serious side effects, including:
Do not take SPRAVATO® if you:
If you are not sure if you have any of the above conditions, talk to your healthcare provider before taking SPRAVATO®.
Before you take SPRAVATO®, tell your healthcare provider about all of your medical conditions, including if you:
Tell your healthcare provider about all the medicines that you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. Taking SPRAVATO® with certain medicine may cause side effects.
Especially tell your healthcare provider if you take central nervous system (CNS) depressants, psychostimulants, or monoamine oxidase inhibitors (MAOIs) medicine. Keep a list of them to show to your healthcare provider and pharmacist when you get a new medicine.
How will I take SPRAVATO®?
What should I avoid while taking SPRAVATO®?
Do not drive, operate machinery, or do anything where you need to be completely alert after taking SPRAVATO®. Do not take part in these activities until the next day following a restful sleep. See “What is the most important information I should know about SPRAVATO®?”
What are the possible side effects of SPRAVATO®?
SPRAVATO® may cause serious side effects including:
See “What is the most important information I should know about SPRAVATO®?”
Increased blood pressure. SPRAVATO® can cause a temporary increase in your blood pressure that may last for about 4 hours after taking a dose. Your healthcare provider will check your blood pressure before taking SPRAVATO® and for at least 2 hours after you take SPRAVATO®. Tell your healthcare provider right away if you get chest pain, shortness of breath, sudden severe headache, change in vision, or seizures after taking SPRAVATO®.
Problems with thinking clearly. Tell your healthcare provider if you have problems thinking or remembering.
Bladder problems. Tell your healthcare provider if you develop trouble urinating, such as a frequent or urgent need to urinate, pain when urinating, or urinating frequently at night.
The most common side effects of SPRAVATO® include:
If these common side effects occur, they usually happen right after taking SPRAVATO® and go away the same day.
These are not all the possible side effects of SPRAVATO®.
Call your doctor for medical advice about side effects. You may report side effects to Johnson & Johnson at 1-800-526-7736, or to the FDA at 1-800-FDA-1088.
What is SPRAVATO® (esketamine) CIII nasal spray?
SPRAVATO® is a prescription medicine used:
SPRAVATO® is not for use as a medicine to prevent or relieve pain (anesthetic). It is not known if SPRAVATO® is safe or effective as an anesthetic medicine.
It is not known if SPRAVATO® is safe and effective for use in preventing suicide or in reducing suicidal thoughts or actions. SPRAVATO® is not for use in place of hospitalization if your healthcare provider determines that hospitalization is needed, even if improvement is experienced after the first dose of SPRAVATO®.
It is not known if SPRAVATO® is safe and effective in children.
Please see full Prescribing Information, including Boxed WARNINGS, and Medication Guide for SPRAVATO® and discuss any questions you may have with your healthcare provider.
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