NeuroStar® TMS Therapy
FDA-cleared, non-medication depression treatment
(855) 940-4867
A couple’s infertility journey can be a long and hard road: the perceived shame surrounding infertility can be very isolating, biological limitations can present a shrinking, anxiety-inducing window of opportunity, treatment itself is expensive, and hormone manipulation can hugely impact mood. It may come as no surprise, then, that experiencing depression while undergoing infertility treatment is common: about 39% of women and 15% of men develop depression during infertility treatment.
Depression is a mental health condition that should be treated, and leaving it untreated can lead to other health problems. However, many patients are concerned with the impact that depression treatments might have on conception and fetal development. Fortunately,[SHM1] there are options available. Read on to learn how infertility and depression are linked, and why you should seek treatment if you're feeling depressed during infertility treatment.
Many people opt to leave depression untreated when they undergo infertility treatment because they are fearful of doing anything that could reduce their chances of getting pregnant or impact the health of their fetus. This worry is understandable, as fertility treatments are a substantial financial investment. The possibility of dealing with the combined side effects of antidepressants and fertility treatment can often be a source of anxiety, too.
Nevertheless, leaving depression untreated is not advisable. Going without treatment can cause the distressing feelings you have to become more intense, and it could even cause persistent physical symptoms, such as nausea, chronic pain, and headaches. In addition to negatively affecting your overall health, depression may even impact your ability to get pregnant. Research has shown that once pregnant,
mothers who experience major depression have an increased risk of premature birth, low birth weight, and decreased fetal growth. After labor
, depression can also make it difficult to bond with the baby.
Infertility and depression are intertwined, and depression can indirectly affect your ability to become pregnant by influencing your overall physical health. For instance, depression sometimes causes a significant increase or decrease in appetite, which could lead to being overweight or underweight. Both states are known to cause or play a part in infertility. Conversely, infertility can cause depression or worsen existing depression. A Harvard study showed that women with infertility feel just as anxious and depressed as people diagnosed with cancer or hypertension. The study also notes that men who are infertile experience similar levels of depression and low self-esteem as infertile women.
As a matter separate from infertility depression, fertility treatment itself can sometimes cause a person to become depressed. For instance, side effects from some of the drugs involved in fertility treatment are depression or other mental health conditions. The financial cost and strain of undergoing fertility treatment can contribute as well, as treatment is not always covered by insurance. The stress of the treatment process itself, which often involves multiple appointments and taking many medications, can also heighten the emotional impact of infertility and contribute to depression.
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Antidepressants are typically the standard treatment for depression. However, some studies suggest that antidepressant use may have a negative impact on fertility, though more research is needed to fully understand their effects. Many people aren't comfortable taking them because they're concerned about either the potential impact on their chances of conceiving or the risk of side effects. In these cases, TMS therapy is a potential non-medication treatment to consider.
Transcranial magnetic stimulation (TMS) therapy delivers gentle magnetic pulses to stimulate the regions of the brain that regulate mood and emotion. The stimulation of nerves in these areas can improve the brain's ability to regulate mood, treating depression. Though TMS has not been studied in large groups of pregnant women, there is no associated impact on hormone levels and the range of the magnetic pulses does not extend to the reproductive system. In addition, TMS therapy has no drug-related side effects and is well-tolerated, so you don't have to worry about extra effects on top of those that may accompany fertility treatments.
There is no need to choose between treating depression and becoming pregnant. There are options, including TMS, that will allow you to do both. If you're interested in learning more, you can continue browsing
resources on TMS, or
reach out to Greenbrook for a consultation. You deserve to feel your best as you work to build a family.
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NeuroStar Adult Indications for Use
The NeuroStar Advanced Therapy System is indicated for the treatment of depressive episodes and for decreasing anxiety symptoms for those who may exhibit comorbid anxiety symptoms in adult patients suffering from Major Depressive Disorder (MDD) and who failed to achieve satisfactory improvement from previous antidepressant medication treatment in the current episode.
The NeuroStar Advanced Therapy System is intended to be used as an adjunct for the treatment of adult patients suffering from Obsessive-Compulsive Disorder (OCD).
NeuroStar Adolescent Indications for Use
NeuroStar Advanced Therapy is indicated as an adjunct for the treatment of Major Depressive Disorder (MDD) in adolescent patients (15-21).
Important Safety Information
NeuroStar Advanced Therapy is only available by prescription. A doctor can help decide if NeuroStar Advanced Therapy is right for you. Patients’ results may vary.
The most common side effect is pain or discomfort at or near the treatment site. These events are transient; they occur during the TMS treatment course and do not occur for most patients after the first week of treatment. There is a rare risk of seizure associated with the use of TMS therapy (<0.1% per patient).
Visit neurostar.com for full safety and prescribing information.
Important Safety Information
What is the most important information I should know about SPRAVATO®?
SPRAVATO® can cause serious side effects, including:
Do not take SPRAVATO® if you:
If you are not sure if you have any of the above conditions, talk to your healthcare provider before taking SPRAVATO®.
Before you take SPRAVATO®, tell your healthcare provider about all of your medical conditions, including if you:
Tell your healthcare provider about all the medicines that you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. Taking SPRAVATO® with certain medicine may cause side effects.
Especially tell your healthcare provider if you take central nervous system (CNS) depressants, psychostimulants, or monoamine oxidase inhibitors (MAOIs) medicine. Keep a list of them to show to your healthcare provider and pharmacist when you get a new medicine.
How will I take SPRAVATO®?
What should I avoid while taking SPRAVATO®?
Do not drive, operate machinery, or do anything where you need to be completely alert after taking SPRAVATO®. Do not take part in these activities until the next day following a restful sleep. See “What is the most important information I should know about SPRAVATO®?”
What are the possible side effects of SPRAVATO®?
SPRAVATO® may cause serious side effects including:
See “What is the most important information I should know about SPRAVATO®?”
Increased blood pressure. SPRAVATO® can cause a temporary increase in your blood pressure that may last for about 4 hours after taking a dose. Your healthcare provider will check your blood pressure before taking SPRAVATO® and for at least 2 hours after you take SPRAVATO®. Tell your healthcare provider right away if you get chest pain, shortness of breath, sudden severe headache, change in vision, or seizures after taking SPRAVATO®.
Problems with thinking clearly. Tell your healthcare provider if you have problems thinking or remembering.
Bladder problems. Tell your healthcare provider if you develop trouble urinating, such as a frequent or urgent need to urinate, pain when urinating, or urinating frequently at night.
The most common side effects of SPRAVATO® include:
If these common side effects occur, they usually happen right after taking SPRAVATO® and go away the same day.
These are not all the possible side effects of SPRAVATO®.
Call your doctor for medical advice about side effects. You may report side effects to Johnson & Johnson at 1-800-526-7736, or to the FDA at 1-800-FDA-1088.
What is SPRAVATO® (esketamine) CIII nasal spray?
SPRAVATO® is a prescription medicine used:
SPRAVATO® is not for use as a medicine to prevent or relieve pain (anesthetic). It is not known if SPRAVATO® is safe or effective as an anesthetic medicine.
It is not known if SPRAVATO® is safe and effective for use in preventing suicide or in reducing suicidal thoughts or actions. SPRAVATO® is not for use in place of hospitalization if your healthcare provider determines that hospitalization is needed, even if improvement is experienced after the first dose of SPRAVATO®.
It is not known if SPRAVATO® is safe and effective in children.
Please see full Prescribing Information, including Boxed WARNINGS, and Medication Guide for SPRAVATO® and discuss any questions you may have with your healthcare provider.
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