NeuroStar® TMS Therapy
FDA-cleared, non-medication depression treatment
(855) 940-4867
Medically reviewed on by
Regional Medical Director Greater St. Louis
Finding the best depression treatment for you requires a clear understanding of your options. At first glance, electroconvulsive therapy (ECT) and transcranial magnetic stimulation (TMS) may seem similar because they both target areas of the brain. However, there are notable differences between the two treatments you should know about, which will allow you to make more informed choices for your mental health and overall well-being.
Depression occurs when there are chemical or structural changes to the brain. The brain contains neurotransmitters, which are the chemical messengers that form a communication network between brain cells. If that system isn’t functioning properly, it can contribute to depression. While there are many different types of neurotransmitters, there are some specific ones that are thought to be linked to depression, such as serotonin, dopamine, glutamate and norepinephrine.
Structural variations in the brain may also play a role in depression, though scientists are uncertain if these alterations are the cause of depression or an effect. These changes to the brain’s structure and chemistry are particularly crucial in the limbic system, which governs mood and behavior, among other functions. Parts of the brain that make up the limbic system include the hippocampus and the amygdala.
Both TMS and ECT treat depression by stimulating areas of the brain. The main difference between TMS therapy vs. ECT is the methodology used in these treatments.
This treatment uses gentle magnetic pulses to stimulate targeted areas of the brain. The pulses create painless electrical currents that activate nerves in the brain. As a result, new connections between nerve cells are formed to restore brain function and ease depression symptoms.
Many people find TMS easy to integrate into their schedules. This is a non-invasive, outpatient treatment, and it is performed without the use of medication or anesthesia.
A typical treatment session lasts between 18 and 45 minutes. An electromagnetic coil is placed on the patient’s scalp, near the left temple. The placement is determined by mapping the patient’s brain, which is done prior to the start of treatment. This ensures that the magnetic pulses hit their target areas in the brain for the greatest effectiveness. Patients stay seated and comfortable during the TMS session, only feeling a slight tapping on their scalp. Patients can return to their normal routines after the session is over.
There are minimal side effects associated with TMS. The most common are mild headaches or some discomfort at the stimulation site on the scalp. These issues can be resolved with over-the-counter pain relievers, which can be taken as needed.
TMS treatments are typically every weekday for a few weeks, and then roughly twice per week near the end of the treatment course. More than 62% of TMS patients experience a significant reduction in symptoms, with 42% of those patients achieving complete remission, according to a study in the Journal of Clinical Psychiatry. Treatment can be repeated if symptoms recur at a later date. TMS can be used on its own or in tandem with an existing medication plan. This decision is made by each individual patient and is based on the recommendations of their primary health care professional and the TMS provider.
There are key differences between TMS treatment vs. ECT. ECT sends low-level electrical currents to the brain that cause a grand mal seizure that typically lasts around 20 to 60 seconds. This seizure is purposely induced because it is thought to improve depression. Patients must go under general anesthesia for ECT treatment and also receive a muscle relaxant to prevent injury from the induced seizure. Unlike TMS, which targets specific areas of the brain involved with depression, ECT seizures affect the entire brain. TMS also doesn’t trigger seizures.
To begin ECT treatment, electrodes are placed on the patient’s head to transmit the electrical current to the brain. Patients are also attached to monitors to check their vital signs during the treatment session. Plus, an electroencephalogram (EEG) tracks brain activity during ECT. The treatment itself takes five to 10 minutes to complete, not including the prep work that must be done before the procedure.
ECT also takes more time post-treatment. Patients must stay for an observation period after ECT, and it can take a few hours (or longer, for some patients) before normal activities are resumed. Patients cannot drive themselves to treatment; with TMS, however, patients aren’t sedated and therefore don’t need to rely on someone else for transportation.
A typical course of ECT treatment includes two to three sessions per week, over three to four weeks. Once completed, ECT can be used with reduced frequency, or patients can employ standard forms of treatment, such as medication or talk therapy, to prevent symptom recurrence.
There are several potential side effects of ECT. These include temporary memory impairment, confusion, headache or muscle pain, and nausea. Physical symptoms can be alleviated with medication. But ECT side effects related to brain function may persist, in some cases for weeks or even months. Memory loss, in particular, can take the form of a temporary amnesia, where patients draw a blank on events before or during treatment. In addition, ECT may not be recommended for people with cardiac conditions because the treatment raises blood pressure and heart rate. The general anesthesia used during ECT can also increase the risk of complications during treatment.
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Now that you know how TMS is different from ECT, you can make a more informed choice. Depression treatment is a personal decision influenced by several factors, such as your age, current health condition, and scheduling availability, as well as the severity of the depression you’re experiencing. We can help you determine
if TMS will be the best fit for you. Our patient consultants will discuss each step of TMS therapy with you, as well as insurance coverage, and you’ll get a treatment plan after meeting with our team of experts.
Find out if TMS therapy is right for you or a loved one. Schedule your free consultation with us today.
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NeuroStar Adult Indications for Use
The NeuroStar Advanced Therapy System is indicated for the treatment of depressive episodes and for decreasing anxiety symptoms for those who may exhibit comorbid anxiety symptoms in adult patients suffering from Major Depressive Disorder (MDD) and who failed to achieve satisfactory improvement from previous antidepressant medication treatment in the current episode.
The NeuroStar Advanced Therapy System is intended to be used as an adjunct for the treatment of adult patients suffering from Obsessive-Compulsive Disorder (OCD).
NeuroStar Adolescent Indications for Use
NeuroStar Advanced Therapy is indicated as an adjunct for the treatment of Major Depressive Disorder (MDD) in adolescent patients (15-21).
Important Safety Information
NeuroStar Advanced Therapy is only available by prescription. A doctor can help decide if NeuroStar Advanced Therapy is right for you. Patients’ results may vary.
The most common side effect is pain or discomfort at or near the treatment site. These events are transient; they occur during the TMS treatment course and do not occur for most patients after the first week of treatment. There is a rare risk of seizure associated with the use of TMS therapy (<0.1% per patient).
Visit neurostar.com for full safety and prescribing information.
Important Safety Information
What is the most important information I should know about SPRAVATO®?
SPRAVATO® can cause serious side effects, including:
Do not take SPRAVATO® if you:
If you are not sure if you have any of the above conditions, talk to your healthcare provider before taking SPRAVATO®.
Before you take SPRAVATO®, tell your healthcare provider about all of your medical conditions, including if you:
Tell your healthcare provider about all the medicines that you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. Taking SPRAVATO® with certain medicine may cause side effects.
Especially tell your healthcare provider if you take central nervous system (CNS) depressants, psychostimulants, or monoamine oxidase inhibitors (MAOIs) medicine. Keep a list of them to show to your healthcare provider and pharmacist when you get a new medicine.
How will I take SPRAVATO®?
What should I avoid while taking SPRAVATO®?
Do not drive, operate machinery, or do anything where you need to be completely alert after taking SPRAVATO®. Do not take part in these activities until the next day following a restful sleep. See “What is the most important information I should know about SPRAVATO®?”
What are the possible side effects of SPRAVATO®?
SPRAVATO® may cause serious side effects including:
See “What is the most important information I should know about SPRAVATO®?”
Increased blood pressure. SPRAVATO® can cause a temporary increase in your blood pressure that may last for about 4 hours after taking a dose. Your healthcare provider will check your blood pressure before taking SPRAVATO® and for at least 2 hours after you take SPRAVATO®. Tell your healthcare provider right away if you get chest pain, shortness of breath, sudden severe headache, change in vision, or seizures after taking SPRAVATO®.
Problems with thinking clearly. Tell your healthcare provider if you have problems thinking or remembering.
Bladder problems. Tell your healthcare provider if you develop trouble urinating, such as a frequent or urgent need to urinate, pain when urinating, or urinating frequently at night.
The most common side effects of SPRAVATO® include:
If these common side effects occur, they usually happen right after taking SPRAVATO® and go away the same day.
These are not all the possible side effects of SPRAVATO®.
Call your doctor for medical advice about side effects. You may report side effects to Johnson & Johnson at 1-800-526-7736, or to the FDA at 1-800-FDA-1088.
What is SPRAVATO® (esketamine) CIII nasal spray?
SPRAVATO® is a prescription medicine used:
SPRAVATO® is not for use as a medicine to prevent or relieve pain (anesthetic). It is not known if SPRAVATO® is safe or effective as an anesthetic medicine.
It is not known if SPRAVATO® is safe and effective for use in preventing suicide or in reducing suicidal thoughts or actions. SPRAVATO® is not for use in place of hospitalization if your healthcare provider determines that hospitalization is needed, even if improvement is experienced after the first dose of SPRAVATO®.
It is not known if SPRAVATO® is safe and effective in children.
Please see full Prescribing Information, including Boxed WARNINGS, and Medication Guide for SPRAVATO® and discuss any questions you may have with your healthcare provider.
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